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ARNISEC 50
₹330.62
ARNISec 50 Tablet is a prescription medication used to treat chronic heart failure in adults with reduced heart pumping function. It works by relaxing blood vessels and improving heart performance, which helps to lower blood pressure and reduce the risk of hospitalization and death.
Key Information
- Active Ingredients: Each tablet contains Sacubitril 24 mg and Valsartan 26 mg, which belong to a class of drugs called angiotensin receptor neprilysin inhibitors (ARNI).
- Administration: It should be taken as advised by a doctor, typically once or twice daily, with or without food, at the same time each day. The tablet should be swallowed whole; do not crush or chew it.
- Mechanism of Action:
- Sacubitril inhibits the enzyme neprilysin, increasing the levels of beneficial peptides that widen blood vessels and reduce fluid retention.
- Valsartan is an angiotensin receptor blocker (ARB) that blocks the action of angiotensin II, a hormone that constricts blood vessels and causes salt/water retention.
- Together, they reduce the strain on the heart and help it pump blood more efficiently.
Potential Side Effects
Common side effects include:
- Low blood pressure (hypotension), which can cause dizziness or lightheadedness.
- High potassium levels in the blood (hyperkalemia).
- Impaired kidney function.
- Cough.
- Diarrhea, nausea, and headache.
Warnings and Precautions
- Pregnancy/Breastfeeding: It is contraindicated during pregnancy and not recommended while breastfeeding, as it can harm the baby.
- Drug Interactions: Do not take this medicine with Angiotensin-Converting Enzyme (ACE) inhibitors (e.g., enalapril) or aliskiren due to an increased risk of severe side effects like angioedema (swelling of the face, lips, tongue, or throat).
- Medical Conditions: Use with caution if you have kidney or liver disease, low blood pressure, or a history of angioedema. Your doctor may monitor your blood pressure, kidney function, and potassium levels regularly.
- Lifestyle: Avoid consuming excessive potassium-rich foods or potassium supplements without consulting a doctor. Limit alcohol intake as it may increase dizziness.
- Do not stop taking ARNISec 50 Tablet without consulting your doctor, even if you feel well, as this may worsen your condition.
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