The combination of Dapagliflozin 10 mg + Vildagliptin 100 mg (SR) tablets is a prescription medication used to manage type 2 diabetes mellitus in adults, typically alongside diet and exercise. “SR” stands for Sustained Release, meaning the Vildagliptin is released slowly over time. 
Key Information
  • Primary Use: Management of high blood sugar (glucose) levels in adults with type 2 diabetes.
  • Mechanism of Action:
    • Dapagliflozin (an SGLT2 inhibitor) helps the kidneys remove excess glucose from the bloodstream through urine.
    • Vildagliptin (a DPP-4 inhibitor) increases the levels of natural substances (incretins) that stimulate the pancreas to produce more insulin after meals and reduce the amount of sugar the liver produces.
  • Administration: It is typically taken orally once daily, with or without food, as directed by a healthcare professional. Tablets should be swallowed whole; do not crush, break, or chew them.
  • Brands: This combination is available under various brand names, such as Vildacag DP, Dapagligen V, Vildalip-D, and Jalra-DP SR, among others. 
Common Side Effects
Most side effects are temporary and disappear as your body adjusts to the medicine. 
  • Urinary tract infections (UTIs)
  • Genital fungal infections (vaginal inflammation or balanitis)
  • Frequent urination
  • Headache, dizziness, tremors, fatigue
  • Nausea or stomach upset
  • Hypoglycemia (low blood sugar), especially when used with other diabetes medications like insulin 
Safety Advice and Warnings
  • Medical Supervision: This medication should only be taken under the guidance and prescription of a qualified healthcare professional.
  • Hydration: It is important to stay well-hydrated when taking this medication to help prevent dehydration and reduce the risk of UTIs.
  • Monitoring: Regular monitoring of blood sugar levels is crucial. Liver function tests may also be required at regular intervals during treatment with vildagliptin.
  • Lifestyle: The medication is part of a complete treatment program that should also include a healthy diet, regular exercise, and weight management.
  • Do not stop taking the medication without consulting your doctor, as this can cause blood sugar levels to rise and increase the risk of serious long-term complications. 

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