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Flunarizine dihydrochloride 10 mg tablets (e.g., brand names Flunarin 10, Sibelium 10, Migarid 10) are a prescription medication primarily used for the prevention of migraines and treatment of vertigo and balance disorders. It is not used for treating an acute migraine attack.
Key Information
- Active Ingredient: Flunarizine (as the dihydrochloride salt) 10 mg.
- Drug Class: Calcium channel blocker with antihistamine and vasodilatory properties.
- Mechanism of Action: It works by blocking the entry of calcium into nerve cells and blood vessels in the brain, which helps prevent the abnormal dilation and over-excitability that can trigger migraines and vertigo.
- Dosage: Typically, one 10 mg tablet is taken once daily at night, as it can cause drowsiness. The dosage may be adjusted by a doctor, or a maintenance schedule (e.g., 5 days on, 2 days off) may be recommended for long-term use.
Common Uses
- Migraine prevention
- Treatment of dizziness and vertigo associated with vestibular disorders
- Management of cerebral blood flow issues (cerebral insufficiency)
Important Precautions & Side Effects
- Common Side Effects: Drowsiness, fatigue, weight gain (due to increased appetite), nausea, constipation, muscle aches, and mood changes (depression).
- Do Not Use If: You have a history of depression, Parkinson’s disease, or liver damage.
- Alcohol: Avoid alcohol consumption while taking this medication as it can increase drowsiness and tiredness.
- Pregnancy/Breastfeeding: Generally not recommended; consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding.
- Driving/Operating Machinery: Use caution, especially when starting treatment, as the medication can cause sleepiness.
Always consult with a healthcare professional before starting or stopping this medication to ensure safe and effective use based on your specific medical condition.
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