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The tablet containing Gliclazide 40 mg, Metformin Hydrochloride 500 mg, and Voglibose 0.2 mg is a prescription medication used to treat Type 2 diabetes mellitus in adults. It is typically prescribed when diet, exercise, and single or dual drug therapies are not sufficient to control blood sugar levels.
How It Works
This is a triple-action combination medicine, with each component working differently to manage blood sugar:
- Gliclazide (a sulfonylurea) stimulates the pancreas to release more insulin.
- Metformin (a biguanide) reduces the amount of glucose produced by the liver, delays glucose absorption from the intestines, and improves the body’s sensitivity to insulin.
- Voglibose (an alpha-glucosidase inhibitor) slows down the breakdown and absorption of complex carbohydrates in the intestines, which helps prevent sudden spikes in blood sugar levels after meals.
Key Information
- Administration: It should be taken orally with food to minimize stomach upset, as directed by a doctor. Do not crush, break, or chew the tablet.
- Lifestyle: The medication is most effective when combined with a healthy diet, regular exercise, and weight management, as advised by your doctor.
- Missed Dose: If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed one and continue with the regular schedule. Do not double up on doses.
- Alcohol: Avoid consuming alcohol while on this medication, as it can increase the risk of dangerously low blood sugar (hypoglycemia) and a rare but serious condition called lactic acidosis.
Common Side Effects
Most side effects are temporary. Consult a doctor if they persist or worsen.
- Hypoglycemia (low blood glucose level), with symptoms such as sweating, dizziness, headache, and shaking.
- Nausea, vomiting, and diarrhea.
- Abdominal pain or discomfort.
- Taste changes.
- Bloating or flatulence.
Serious Warnings
- This medication is not suitable for people with Type 1 diabetes, severe kidney or liver disease, or diabetic ketoacidosis.
- Long-term use of Metformin may lead to Vitamin B12 deficiency, which may require supplementation as advised by your doctor.
- Rare but serious side effects include lactic acidosis (symptoms include muscle pain, trouble breathing, unusual weakness) and severe allergic reactions. Seek immediate medical attention if you experience these symptoms.
Always consult a healthcare professional for personalized medical advice regarding dosage, side effects, and interactions, as this is a prescription medication.
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