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Glipizide (5mg) + Metformin (500mg) Tab USP
₹21.80
The tablet containing Glipizide (5 mg) + Metformin (500 mg) Tab USP is a prescription medication used to treat type 2 diabetes mellitus in adults. It works by combining two different mechanisms to control blood sugar levels when diet and exercise alone are insufficient.
Key Information
- Active Ingredients: Glipizide (5 mg) and Metformin Hydrochloride (500 mg). “USP” indicates that the ingredients meet the standards of the United States Pharmacopeia.
- Purpose: To improve glycemic control (blood sugar levels) in adults with type 2 diabetes. It is not for type 1 diabetes or diabetic ketoacidosis.
- Mechanism: Glipizide stimulates the pancreas to release more insulin, while metformin decreases glucose production in the liver, reduces sugar absorption from the intestines, and improves the body’s sensitivity to insulin.
How to Use
- Administration: Take this medication orally with a meal, typically once or twice daily, as directed by a healthcare provider. Taking it with food helps reduce gastrointestinal side effects.
- Dosage: The dose is determined by a doctor and can be adjusted based on blood sugar levels. Do not exceed the maximum recommended doses (generally 40 mg of glipizide and 2000 mg of metformin per day).
- Important Note: Do not stop taking this medicine without consulting your doctor, even if you feel well, as blood sugar levels could rise and cause complications.
Potential Side Effects and Warnings
Common side effects often include low blood sugar (hypoglycemia), diarrhea, nausea, and stomach pain.
Serious, though rare, side effects include:
- Lactic Acidosis: A buildup of lactic acid in the blood, which is a medical emergency. Symptoms include muscle pain, difficulty breathing, unusual tiredness, and abdominal pain. The risk is higher in people with kidney impairment, excessive alcohol intake, or certain other conditions.
- Hypoglycemia (low blood sugar): Symptoms include sweating, dizziness, headache, and shaking. Always carry a fast-acting source of glucose (like fruit juice or sugary candy) to treat this.
- Vitamin B12 Deficiency: Long-term use of metformin can lead to a decrease in Vitamin B12 levels, which may cause anemia or nerve problems. Regular blood tests are advised.
Consult your doctor if you have a history of:
- Kidney or liver disease.
- Heart disease.
- Severe infection, trauma, or are scheduled for surgery or a radiological procedure with contrast dye, as the medication may need to be temporarily stopped.
- Are pregnant or breastfeeding.
For more information on the medication, its interactions, and potential risks, refer to the FDA drug label information or consult a healthcare professional.
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