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Glipizide (5mg) + Metformin (500mg) Tab USP
₹21.80
The Glipizide 5 mg + Metformin 500 mg Tablet (USP/IP) is a prescription combination medicine used to treat Type 2 diabetes mellitus in adults. It helps control high blood sugar levels when diet and exercise alone are insufficient.
Active Ingredients and How They Work
This tablet combines two different types of anti-diabetic medications:
- Glipizide (5 mg): This belongs to the sulfonylurea class of drugs. It primarily works by stimulating the pancreas to release more insulin into the bloodstream, especially after meals, which helps lower blood sugar levels.
- Metformin Hydrochloride (500 mg): This belongs to the biguanide class. It has three actions: it reduces the amount of glucose produced by the liver, it delays glucose absorption from the intestines, and it increases the body’s sensitivity to its own insulin.
Key Uses and Benefits
- Blood Sugar Control: Effectively manages blood glucose levels in adults with type 2 diabetes.
- Prevention of Complications: By keeping blood sugar levels stable, it helps reduce the long-term risk of serious diabetes complications like kidney damage, vision problems, nerve damage (neuropathy), and heart conditions.
- Dual Action: Provides a comprehensive approach to diabetes management by addressing insulin production and insulin resistance simultaneously.
Potential Side Effects and Precautions
Common Side Effects:
- Hypoglycemia (low blood sugar levels), symptoms include sweating, dizziness, headache, and shaking.
- Gastrointestinal issues: Nausea, diarrhea, stomach pain, or altered taste.
- Headache, dizziness, or upper respiratory tract infection.
Serious but Rare Side Effects:
- Lactic Acidosis: A rare but serious metabolic complication of metformin accumulation, which can be life-threatening. Symptoms include muscle pain or weakness, difficulty breathing, feeling cold, dizziness, and severe stomach pain. Seek immediate medical attention if these symptoms occur.
- Vitamin B12 Deficiency: Long-term use of metformin may interfere with B12 absorption.
Important Precautions:
- Prescription Required: This is a prescription medicine and must be taken exactly as prescribed by your doctor.
- Take with Food: Always take this medicine with or just before meals to reduce stomach upset and the risk of low blood sugar.
- Alcohol Avoidance: Avoid drinking alcohol as it increases the risk of low blood sugar and lactic acidosis.
- Monitoring: Regular monitoring of blood sugar levels, liver function, and kidney function is advised by your doctor.
- Pregnancy/Breastfeeding: It is generally not recommended during pregnancy or breastfeeding; consult your doctor if you are pregnant or planning to conceive.
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