Glycomet 500 SR Tablet is a prescription medication containing Metformin Hydrochloride (500mg), primarily used to treat type 2 diabetes mellitus and polycystic ovary syndrome (PCOS) in women. The “SR” stands for sustained release, meaning the medication is released slowly into the body to provide a more consistent effect and reduce side effects. 
Key Details
  • Active Ingredient: Metformin Hydrochloride (500 mg)
  • Manufacturer: USV Pvt Ltd.
  • Mechanism of Action: It works by decreasing the amount of glucose produced by the liver, enhancing the body’s sensitivity to insulin, and slowing down the absorption of sugar from the intestines.
  • Administration: The tablet should be swallowed whole with a glass of water, usually with or after meals to minimize gastrointestinal side effects. It must not be crushed, chewed, or broken.
  • Dosage: The dosage is determined by a doctor based on the patient’s condition. It is typically taken once or twice daily at the same time each day. 
Uses
  • Type 2 Diabetes Mellitus: Helps control high blood sugar levels and prevents serious complications like kidney damage, eye problems, nerve issues, and the risk of heart attack or stroke.
  • Polycystic Ovary Syndrome (PCOS): Manages PCOS by improving insulin sensitivity, which helps regulate menstrual cycles, improve ovulation, and reduce symptoms like acne and excess hair growth. 
Common Side Effects
Most side effects are generally mild and temporary, resolving as the body adjusts to the medication. 
  • Diarrhea
  • Nausea and vomiting
  • Abdominal pain or discomfort
  • Loss of appetite
  • Metallic taste in the mouth
  • Headache
  • Vitamin B12 deficiency (with long-term use) 
A rare but serious side effect is lactic acidosis, which requires immediate medical attention. Symptoms include unusual muscle pain, difficulty breathing, severe tiredness, and stomach pain. 
Warnings and Precautions
  • Alcohol: Avoid excessive alcohol consumption, as it increases the risk of lactic acidosis.
  • Kidney/Liver Problems: Use with caution in patients with kidney or liver disease. It is generally not recommended in cases of severe impairment.
  • Pregnancy and Breastfeeding: Consult a doctor before use, as caution is advised. The doctor will weigh the benefits and potential risks.
  • Interactions: Inform your doctor about all other medications you are taking, especially insulin, diuretics, or anti-inflammatory drugs, to avoid interactions.
  • Lifestyle: The medication works best when combined with a healthy diet and regular exercise program. 

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