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Human Mixtard 40IU is an injectable prescription medication containing a combination of insulins, used to treat type 1 and type 2 diabetes mellitus. It helps manage blood sugar levels throughout the day by combining both fast-acting and intermediate-acting insulin.
Key Ingredients and Action
Human Mixtard 40IU is a biphasic isophane insulin (recombinant human insulin) formulation that comes in a 10ml vial or pen. The “40IU/ml” indicates its concentration (40 International Units per milliliter).
It contains two types of insulin in a 30/70 ratio:
- Human Insulin (Regular/Soluble – 30%): A short-acting insulin that begins to lower blood sugar levels within 30 minutes to control post-meal sugar spikes.
- Insulin Isophane (NPH/Isophane – 70%): An intermediate-acting insulin that continues to work for an extended period, helping to keep blood sugar levels stable between meals and overnight.
Uses and Benefits
- Blood Sugar Control: Helps maintain consistent blood glucose control in diabetic patients.
- Diabetes Management: Used as part of a comprehensive treatment plan including diet, exercise, and weight management.
- Prevents Complications: By controlling blood sugar levels, it helps prevent long-term complications of diabetes such as diabetic neuropathy or retinopathy.
Important Precautions and Administration
- Prescription Only: Use only under the supervision and guidance of a doctor.
- Administration: Injected subcutaneously (under the skin) in the thigh, upper arm, abdomen, or buttocks.
- Timing: The injection should be administered 30 minutes before a meal.
- Injection Site Rotation: Rotate injection sites within the same general area to reduce the risk of skin thickening or pits (lipodystrophy).
- Storage: Unopened vials must be stored in a refrigerator between 2°C and 8°C. Do not freeze.
- Do Not Stop Abruptly: Do not stop taking the medicine without consulting your doctor, as symptoms may reoccur.
Common Side Effects
The most common side effect is hypoglycemia (low blood sugar levels). Symptoms include sweating, shakiness, hunger, dizziness, and a fast heartbeat. Other common side effects include:
- Pain, redness, itching, or swelling at the injection site
- Weight gain
- Fluid retention (edema)
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