Intagesic-MR Tablet is a prescription combination medicine used to relieve pain, inflammation, and muscle spasms associated with musculoskeletal conditions such as back pain, sprains, and arthritis. It is manufactured by Intas Pharmaceuticals Ltd.. 
Key Ingredients and Action
Intagesic-MR Tablet combines three active ingredients that provide a multi-faceted approach to pain management: 
  • Diclofenac Sodium (50 mg): A non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by blocking the production of chemical messengers called prostaglandins at the site of injury.
  • Paracetamol (Acetaminophen) (325 mg): An analgesic (pain reliever) and antipyretic (fever reducer) that enhances the overall pain relief effect by acting mainly on the central nervous system.
  • Chlorzoxazone (250 mg): A muscle relaxant that works on the centers in the brain and spinal cord to relieve muscle stiffness and spasms, thereby improving muscle movement. 
Uses and Benefits
Intagesic-MR Tablet is prescribed for various painful conditions: 
  • Treatment of muscle spasms and associated pain.
  • Musculoskeletal pain due to tissue injury, strains, or sprains.
  • Joint pain related to conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
  • Relief from backache and neck pain.
  • Pain and inflammation following surgeries. 
Important Precautions
  • Prescription Required: Use only as directed by a healthcare professional.
  • Take with Food: Always take the tablet with food or milk to reduce the risk of stomach upset or irritation.
  • Avoid Alcohol: Consuming alcohol while on this medication can increase the risk of excessive drowsiness and liver damage.
  • Do Not Drive: The medicine can cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.
  • Do Not Take with Other Painkillers: Avoid taking other medicines containing paracetamol or diclofenac to prevent an overdose or potential kidney/liver damage.
  • Pregnancy and Breastfeeding: It is generally not recommended during pregnancy or breastfeeding. Consult a doctor for advice. 
Potential Side Effects
Common side effects are generally mild and go away as the body adjusts: 
  • Nausea and vomiting
  • Abdominal pain or indigestion/heartburn
  • Diarrhea or constipation
  • Dizziness and drowsiness
  • Dry mouth 
Consult a doctor if side effects persist or worsen. 

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