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The Methotrexate 7.5 mg tablet is a prescription medication used to treat certain types of cancer, severe rheumatoid arthritis, and severe psoriasis, by slowing cell growth and suppressing the immune system.
Active Ingredient
- Methotrexate (7.5 mg): This potent medicine belongs to a class of drugs called antimetabolites. It works by inhibiting an enzyme crucial for DNA synthesis and cell division. In autoimmune conditions like arthritis and psoriasis, it suppresses the overactive immune system to reduce inflammation and pain; in cancer treatment, it stops the rapid growth of cancer cells.
Key Uses and Benefits
Methotrexate 7.5 mg tablets are primarily used when other treatments have been ineffective:
- Rheumatoid Arthritis: Manages symptoms like joint inflammation, pain, and stiffness, and helps prevent long-term joint damage.
- Psoriasis: Treats severe cases of psoriasis by slowing down the excessive production of skin cells, which reduces scaling, redness, and thickness of psoriatic plaques.
- Cancer Treatment: It is part of chemotherapy regimens for various cancers, including leukemia, lymphoma, and solid tumors in the breast, lung, head, and neck.
- Crohn’s Disease: Helps reduce inflammation and manage symptoms in this chronic inflammatory bowel disease.
Potential Side Effects and Precautions
Common Side Effects:
- Nausea and vomiting
- Mouth sores or ulcers (ulcerative stomatitis)
- Fatigue and dizziness
- Hair loss
- Abdominal pain or discomfort
- Low blood cell count (anemia, increased infection risk)
Important Precautions:
- Prescription Only: It must be used under strict medical supervision. The dosage is typically taken once a week, not daily. Taking more than prescribed can be toxic.
- Pregnancy and Breastfeeding: Methotrexate is highly unsafe during pregnancy or while breastfeeding due to the significant risk of harm to the baby. Effective contraception is required during treatment and for a period afterward.
- Alcohol: Avoid consuming alcohol, as it significantly increases the risk of liver damage.
- Folic Acid: Your doctor may advise taking folic acid supplements to help reduce certain side effects, like mouth ulcers and nausea.
- Monitoring: Regular blood tests are essential to monitor liver and kidney function and blood cell counts during treatment.
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