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The medication combining Methylcobalamin 1500 mcg and Pregabalin 75 mg (SR) tablets is a prescription drug primarily used to treat neuropathic pain (nerve pain). It is available under various brand names, such as Pregalin M SR 75, Pregab M, and Genericart Methylcobalamin+Pregabalin.
Key Information
- Uses: This combination is indicated for chronic pain caused by nerve damage due to conditions like diabetes (diabetic neuropathy), shingles (postherpetic neuralgia), or spinal cord injury. It helps reduce pain, tingling, numbness, and associated symptoms like sleep problems and mood changes.
- Mechanism of Action:
- Pregabalin: This ingredient is an anticonvulsant that works by modulating calcium channels in nerve cells, which decreases the release of pain signals in the brain.
- Methylcobalamin: This is a form of Vitamin B12 that helps in the production of myelin, a substance that protects and helps regenerate damaged nerve fibers.
- Administration:
- It is a sustained-release (SR) formulation, designed to provide all-day action.
- It should be taken in the dose and duration advised by a doctor.
- It can be taken with or without food, preferably at the same time each day.
- Crucially, the tablet should be swallowed whole; it should not be chewed, crushed, or broken.
- Important Precautions:
- Prescription Required: This is a prescription-only medication and should only be used under medical supervision.
- Do Not Stop Abruptly: Do not stop taking this medicine suddenly without consulting your doctor, as it can cause withdrawal symptoms like anxiety, pain, and sleeping difficulties.
- Side Effects: Common side effects include dizziness, drowsiness, blurred vision, weight gain, and dry mouth.
- Alcohol: Avoid consuming alcohol while on this medication, as it can cause excessive sleepiness and increase the risk of side effects.
- Driving: Due to potential dizziness and drowsiness, avoid driving or operating heavy machinery until you know how the medicine affects you.
- Pregnancy/Breastfeeding: Consult a healthcare professional before use if you are pregnant or breastfeeding.
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