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PROLUTON-DEPOT 250 INJ
₹278.30
Proluton Depot 250 mg Injection is a prescription medication containing the female hormone hydroxyprogesterone (250 mg), primarily used to prevent premature labor and miscarriage in pregnant women with a history of preterm delivery. It is administered only by a healthcare professional.
Key Information
- Active Ingredient: Each 1 ml injection contains hydroxyprogesterone caproate 250 mg.
- Mechanism of Action: It is a synthetic form of the natural hormone progesterone, which is vital for a healthy pregnancy. It works by thickening the lining of the uterus, preventing strong contractions that can lead to premature labor, and modulating the immune response to support the attachment and growth of the embryo/fetus.
- Uses:
- To lower the risk of recurrent preterm birth in women who have had a previous spontaneous preterm delivery.
- To prevent miscarriage in early pregnancy (primarily when a hormone deficiency is the cause).
- To manage premature labor when symptoms first appear.
Administration and Precautions
- Administration: The injection is administered by a doctor or trained nurse, either into a muscle (intramuscular) or under the skin (subcutaneously). It should not be self-administered. The dose is typically given weekly, usually starting between 16 and 20 weeks of pregnancy and continuing through week 37, or until delivery.
- Common Side Effects: Most side effects are temporary and include pain, swelling, itching, or a hard lump at the injection site, nausea, diarrhea, and skin rash.
- Precautions:
- Contraindications: Avoid this medicine if you have liver problems (including liver tumors or jaundice during pregnancy), uncontrolled high blood pressure, a history of blood clots, or known or suspected breast/hormone-sensitive cancer.
- Medical Conditions: Use with caution if you have diabetes, kidney problems, asthma, epilepsy, migraine, or a history of depression, as regular monitoring may be required.
- Pregnancy/Breastfeeding: It is generally considered safe when prescribed during pregnancy. Consult your doctor if breastfeeding, as small amounts may pass into breast milk.
- Alcohol: There is limited information on alcohol interaction, but it is best to consult your doctor and avoid alcohol consumption.
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