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Sacubitril 49 mg + Valsartan 51 mg Tabs (Swasartan 49/51) – GA
₹417.00
The tablet containing Sacubitril 49 mg and Valsartan 51 mg is a prescription medication primarily used to treat chronic heart failure in adults and children (one year and older) to reduce the risk of hospitalization and cardiovascular death.
Key Information
- Primary Use: Treatment of chronic heart failure with reduced ejection fraction (HFrEF), a condition where the heart’s left ventricle does not pump blood efficiently.
- Mechanism of Action: It is an Angiotensin Receptor-Neprilysin Inhibitor (ARNI). Sacubitril inhibits the enzyme neprilysin to increase beneficial peptides that relax blood vessels and reduce fluid retention. Valsartan is an angiotensin receptor blocker (ARB) that further relaxes blood vessels and lowers blood pressure. This dual action reduces the workload on the heart and improves its function.
- Administration: It is taken orally, typically twice daily, with or without food. The dose may be adjusted by a doctor based on patient tolerance and response.
- Important Precaution: A 36-hour washout period is required when switching from an ACE inhibitor (another class of heart medication) to this drug to avoid a serious side effect called angioedema (swelling of the face, lips, tongue, or throat).
Common Side Effects
- Low blood pressure (hypotension), which may cause dizziness.
- High potassium levels in the blood (hyperkalemia).
- Cough.
- Impaired kidney function (renal impairment).
- Dizziness or lightheadedness.
Warnings and Precautions
- Pregnancy: The medication can cause injury or death to an unborn baby and should not be used during pregnancy.
- Drug Interactions: Inform your doctor about all other medications, especially ACE inhibitors, potassium supplements, or other blood pressure medications, as interactions can occur.
- Monitoring: Regular monitoring of blood pressure, kidney function, and potassium levels is recommended during treatment.
- Alcohol: Alcohol consumption may increase the risk of dizziness and should be limited or avoided.
Always consult with a qualified healthcare professional before starting or stopping any medication to ensure it is appropriate for your specific medical condition.
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