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Teneligliptin 20 mg + Metformin 500 mg Tabs- (TENESWAS M 20/500)GA
₹73.47
The combination of Teneligliptin 20 mg + Metformin 500 mg (often extended-release or SR formulation) is an oral prescription medication used to manage blood sugar levels in adults with type 2 diabetes mellitus. It is used as an adjunct to diet and exercise, particularly when diet and exercise alone, or metformin alone, do not provide adequate glycemic control.
Key Details
- Active Ingredients: Teneligliptin (20 mg), a dipeptidyl peptidase-4 (DPP-4) inhibitor, and Metformin Hydrochloride (500 mg), a biguanide.
- Mechanism of Action: Metformin lowers glucose production in the liver, increases the body’s sensitivity to insulin, and delays glucose absorption from the intestines. Teneligliptin works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels, especially after meals.
- Dosage: Typically taken orally once or twice daily with meals to minimize stomach upset, as directed by a healthcare provider. Tablets should be swallowed whole and not crushed or chewed.
Potential Side Effects
Most side effects are common and tend to resolve as the body adjusts to the medication. Consult a doctor if any persist or worsen.
- Common Side Effects
- Nausea, vomiting, and diarrhea
- Stomach upset, abdominal pain, bloating, and flatulence
- Headache, fatigue
- Low blood sugar (hypoglycemia), especially if combined with other diabetes medications like insulin or sulfonylureas
- Altered taste sensations
- Nasal congestion, sore throat, or respiratory infection
- Serious (but rare) Side Effects
- Lactic acidosis: A potentially life-threatening condition involving the build-up of lactic acid in the blood, characterized by symptoms like deep or rapid breathing, persistent nausea/vomiting, stomach pain, muscle cramps, and unusual tiredness. The risk is higher with kidney impairment, liver disease, or excessive alcohol consumption.
- Vitamin B12 deficiency: Long-term use may lead to vitamin B12 deficiency, which can cause anemia and nerve problems.
- Allergic reactions: Serious reactions like hives, swelling of the face, lips, tongue, or throat can occur.
Important Precautions
- Medical Conditions: Inform your doctor about pre-existing kidney, liver, or heart problems.
- Alcohol: Avoid consuming alcohol as it increases the risk of lactic acidosis and hypoglycemia.
- Pregnancy/Breastfeeding: Not generally recommended during pregnancy or breastfeeding; consult your doctor.
- Monitoring: Regular monitoring of blood sugar levels and kidney function is essential during treatment.
- Other Medications: Inform your doctor about all other medicines you are taking to prevent potential drug interactions.
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