Ursodeoxycholic acid (also known as ursodiol) 150 mg tablets are a prescription medication used to dissolve certain types of gallstones and to treat a specific type of chronic liver disease called primary biliary cholangitis (PBC)
Key Information
  • Active Ingredient: Ursodeoxycholic acid (UDCA) is a naturally occurring bile acid that helps regulate cholesterol and protect liver cells.
  • Uses:
    • Dissolving cholesterol-based gallstones in patients who cannot undergo surgery.
    • Treating primary biliary cholangitis (PBC) to prevent or delay liver damage.
    • Managing liver and biliary diseases associated with cystic fibrosis in children aged 6 to 18 years.
  • How it Works: It reduces the amount of cholesterol produced by the liver and absorbed by the intestines, which helps break down cholesterol gallstones. It also improves bile flow and protects liver cells from toxic bile acids.
  • Administration: The tablets should be swallowed whole with a glass of water or milk, usually after a meal. The dosage and timing (often with the evening meal) are determined by your doctor based on your body weight and condition. 
Common Side Effects
Most side effects are mild and resolve as your body adjusts to the medication. Consult your doctor if they persist. 
  • Abdominal pain or discomfort
  • Diarrhea
  • Nausea
  • Hair loss or rash 
Important Precautions
  • Prescription Required: This is a prescription medicine and should only be used under medical supervision.
  • Alcohol: Avoid consuming alcohol as it may increase the risk of liver damage.
  • Pregnancy/Breastfeeding: Consult your doctor before using this medicine if you are pregnant or breastfeeding, as its safety has not been fully established.
  • Drug Interactions: UDCA can interact with other medications, including certain antacids and oral contraceptives. Inform your doctor about all medicines you are taking.
  • Monitoring: Your doctor may request regular blood tests and ultrasound scans to monitor your liver function and the progress of the treatment. 

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