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Zyloric tablets are a prescription medication containing allopurinol as the active ingredient, primarily used to treat and prevent gout and conditions caused by high uric acid levels in the body. It helps lower uric acid levels in the blood and urine to prevent crystal formation in joints and kidneys.
Key Information
- Active Ingredient: Each tablet contains allopurinol (available in 100 mg and 300 mg strengths).
- Mechanism of Action: Allopurinol is a xanthine oxidase inhibitor, meaning it blocks the enzyme responsible for producing uric acid. This reduces the overall amount of uric acid in the body, which helps prevent the formation of painful crystals in the joints (gout) and kidneys (kidney stones).
- Uses:
- Treatment and prevention of gout (gouty arthritis).
- Prevention of uric acid kidney stones and bladder stones.
- Management of high uric acid levels caused by certain cancer treatments (chemotherapy).
- Administration:
- Take the tablet as a whole with food to minimize stomach upset.
- The medicine is usually prescribed once daily, but doses exceeding 300 mg or if stomach upset occurs, can be taken in divided doses as advised by a doctor.
- Drink plenty of fluids (2-3 liters of water daily) while on treatment to help prevent kidney stones.
- Do not stop taking the medicine suddenly, even during a gout attack, as this may worsen symptoms; continue as prescribed by your doctor.
Potential Side Effects and Precautions
- Common Side Effects: Most side effects are temporary and mild, including skin rash, diarrhea, nausea, vomiting, stomach upset, and drowsiness.
- Serious Precautions:
- Allergic Reactions: Stop taking the tablet immediately and contact a doctor if you develop a skin rash, blistering, or signs of a severe allergic reaction (Stevens-Johnson syndrome or DRESS syndrome).
- Organ Issues: Inform your doctor if you have existing kidney or liver disease, heart problems, or thyroid problems, as dose adjustments or close monitoring may be required.
- Pregnancy/Breastfeeding: Generally not recommended during pregnancy or breastfeeding; consult a doctor.
- Alcohol: Avoid consuming alcohol, as it can increase uric acid levels and worsen gout.
- Driving: The medication may cause dizziness or drowsiness, so exercise caution when driving or operating machinery.
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