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BACTRIM DS (Double Strength) is a prescription combination antibiotic medication that contains two active ingredients: sulfamethoxazole (800 mg) and trimethoprim (160 mg). It is used to treat a variety of bacterial infections by stopping the growth and spread of bacteria.
Key Information
- Active Ingredients: Sulfamethoxazole (a sulfonamide) and Trimethoprim (a folic acid inhibitor).
- Mechanism of Action: The two ingredients work synergistically by blocking two sequential steps in the bacterial synthesis of folic acid, a substance essential for bacteria to produce DNA and proteins and thus survive and multiply.
- “DS” Designation: The “DS” stands for “Double Strength,” indicating a higher concentration of active ingredients compared to the regular-strength Bactrim formulation.
- Form: It is primarily available as an oral tablet, but also as an oral liquid suspension and injection (generic form).
Common Uses
BACTRIM DS is prescribed for bacterial infections in various parts of the body:
- Urinary tract infections (UTIs)
- Respiratory tract infections such as bronchitis and certain types of pneumonia (including Pneumocystis jirovecii pneumonia, or PJP, especially in immunocompromised patients)
- Ear infections (otitis media) in children (usually when other options aren’t suitable)
- Shigellosis and traveler’s diarrhea (gastrointestinal infections)
- Skin and soft tissue infections, including some cases of MRSA
Important Considerations
BACTRIM DS treats bacterial infections only. Finish the entire prescribed course of medication. Stay well-hydrated to help prevent kidney issues. Common side effects may include nausea, vomiting, diarrhea, headache, and rash. Serious side effects are rare but possible; seek medical attention for severe symptoms. BACTRIM DS is not suitable for individuals with certain conditions, including known sulfa drug hypersensitivity, severe liver or kidney disease, or documented folate deficiency anemia, or for infants under two months old. Always consult a healthcare provider for diagnosis and treatment and inform them of your complete medical history and current medications.
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