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Methotrexate 7.5 mg tablets are a potent, prescription-only medication primarily used to treat certain cancers and severe autoimmune diseases like rheumatoid arthritis and psoriasis. It is usually taken once a week, not daily, and requires regular medical supervision due to potential toxicity.
Key Information
- Active Ingredient: Methotrexate (7.5 mg).
- Drug Class: Antimetabolite and immunosuppressant.
- Administration: Taken orally, swallowed whole with a glass of water, with or without food. It is crucial to follow the doctor’s specific weekly schedule to avoid serious harm.
Uses
Methotrexate works by slowing the growth of rapidly dividing cells and suppressing an overactive immune system.
- Rheumatoid Arthritis: Used for severe cases when other treatments have failed, it helps reduce inflammation, pain, stiffness, and joint damage.
- Psoriasis: Used to manage severe psoriasis by slowing the rapid production of skin cells.
- Cancer: Used alone or in combination with other medicines to treat various cancers, including certain leukemias, non-Hodgkin’s lymphoma, and solid tumors in the breast, lung, and head and neck.
- Crohn’s Disease: Helps reduce inflammation in the intestines and manage symptoms.
Important Safety Information
- Prescription Required: This medication is only available with a doctor’s prescription.
- Dosage Frequency: For autoimmune conditions, it is typically a once-weekly dose. Taking it daily can be fatal.
- Folic Acid Supplementation: Your doctor will likely prescribe folic acid to be taken with methotrexate to reduce common side effects like mouth ulcers and nausea.
- Avoid Alcohol: Consuming alcohol while taking methotrexate significantly increases the risk of liver damage.
- Pregnancy/Breastfeeding: It is highly unsafe during pregnancy as it can harm the baby. Use effective contraception during and for a specified period after treatment.
- Monitoring: Regular blood tests are essential to monitor your liver function, kidney function, and blood cell counts during treatment.
Common Side Effects
- Nausea and vomiting.
- Mouth sores or ulcers.
- Fatigue and dizziness.
- Hair loss (usually temporary).
If you experience severe symptoms like difficulty breathing, unusual bleeding, dark urine, or signs of infection (fever, persistent sore throat), seek medical attention immediately.
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