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Ondansetron 4 mg Orally Disintegrating Tab
₹55.00
Ondansetron 4 mg orally disintegrating tablets (ODT), commonly known by the former brand name Zofran ODT, are a prescription antiemetic medication used to prevent nausea and vomiting. The tablets dissolve rapidly on the tongue without needing water, which makes them easy to take.
Key Information
- Primary Uses: Prevention of nausea and vomiting caused by cancer chemotherapy, radiation therapy, and after surgery.
- Mechanism of Action: It works by blocking serotonin, a natural substance in the body and brain that can trigger the vomiting reflex.
- Administration: The tablet is placed immediately on top of the tongue, where it dissolves in seconds, and is then swallowed with saliva. Hands must be dry when handling the tablet, and it should not be pushed through the foil packaging.
- Common Side Effects: Headache, constipation, diarrhea, fatigue, and dizziness.
- Important Warnings:
- It should not be used with apomorphine due to the risk of profound low blood pressure and loss of consciousness.
- It can affect heart rhythm (QT prolongation), especially in patients with existing heart conditions or electrolyte abnormalities (like low potassium or magnesium).
- It may mask symptoms of a stomach or bowel blockage (ileus).
- The ODT formulation contains phenylalanine (a component of aspartame) and should not be used by individuals with phenylketonuria (PKU).
Dosage
The dosage is determined by a doctor based on the patient’s condition and treatment type.
- For moderately emetogenic chemotherapy in adults: Typically 8 mg 30 minutes before treatment, followed by another 8 mg dose 8 hours later, then 8 mg twice a day for 1 to 2 days after chemotherapy completion.
- For radiation therapy in adults: Typically 8 mg taken 1 to 2 hours before treatment, with subsequent doses every 8 hours.
- For prevention of postoperative nausea/vomiting in adults: A single 16 mg dose one hour before anesthesia.
Always follow your doctor’s instructions precisely and inform them of all medications, supplements, and health conditions you have to avoid potential interactions or complications.
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