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Ondansetron 4 mg Orally Disintegrating Tab
₹57.40
Ondansetron 4 mg orally disintegrating tablets (ODT) are a prescription antiemetic medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery.
Key Information
- Active Ingredient: Ondansetron (4 mg base).
- Mechanism of Action: It is a selective serotonin 5-HT3 receptor antagonist, working by blocking a chemical messenger (serotonin) in the brain and gut that triggers the vomiting reflex.
- Administration: The ODT form is designed to dissolve rapidly on the tongue without needing water for swallowing.
How to Take It
Follow your doctor’s instructions carefully.
- Ensure your hands are dry before handling the tablet.
- Do not push the tablet through the foil backing. Instead, peel back the foil backing of the blister pack.
- Gently remove the tablet and immediately place it on top of your tongue.
- It will dissolve in seconds and can be swallowed with your saliva.
- It can be taken with or without food.
Common Uses
Ondansetron ODT is FDA-approved for:
- Chemotherapy-induced nausea and vomiting (CINV): Used for moderately to highly emetogenic chemotherapy regimens.
- Radiation-induced nausea and vomiting: Used for patients receiving total body or abdominal radiation.
- Postoperative nausea and vomiting (PONV): Used for prevention after surgery.
Potential Side Effects and Warnings
Common side effects often include headache, constipation, or fatigue.
Serious side effects are rare, but include:
- Heart rhythm changes: It may cause QT prolongation, a rare heart rhythm problem. Patients with heart conditions or electrolyte imbalances (low potassium or magnesium) should be monitored.
- Serotonin Syndrome: A potentially life-threatening condition that can occur, especially when combined with other serotonergic drugs like certain antidepressants or migraine medications. Symptoms include agitation, hallucinations, rapid heart rate, and muscle stiffness.
- Masking of intestinal blockage: It may mask symptoms of a progressive ileus (bowel blockage) after abdominal surgery.
- Allergic reactions: Seek emergency help if you experience a rash, hives, swelling, or difficulty breathing.
- Phenylketonuria (PKU): The ODT formulation contains phenylalanine (a component of aspartame) and should not be used by individuals with PKU without consulting a doctor.
Always consult your doctor or pharmacist regarding specific concerns, drug interactions, or if side effects persist.
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