Tofanol 5 mg tablets contain the active ingredient tofacitinib and are primarily used to treat various autoimmune inflammatory disorders. This is a prescription medication that works by modulating the immune system. 
Key Information
  • Active Ingredient: Tofanol 5 mg tablets contain tofacitinib (5 mg).
  • Mechanism of Action: Tofacitinib is a Janus kinase (JAK) inhibitor. It works by blocking the action of JAK enzymes, which are involved in the inflammation that causes symptoms in certain chronic conditions.
  • Manufacturer: The manufacturer for the Tofanol brand of tofacitinib is listed as Knoll by several sources.
  • Prescription Status: This medication is a prescription drug and should be used under medical supervision. 
Uses
Tofanol 5 mg is used to treat moderate to severe forms of the following conditions, typically in adults who have not responded well to other therapies like TNF inhibitors: 
  • Rheumatoid arthritis: A condition causing pain, swelling, and loss of joint function.
  • Psoriatic arthritis: A type of arthritis that affects some individuals with psoriasis, causing joint pain, stiffness, and swelling.
  • Ankylosing spondylitis: A form of arthritis that mainly affects the spine and large joints.
  • Ulcerative colitis: A condition causing swelling and sores (ulcers) in the lining of the colon and rectum. 
Common Side Effects
Common side effects of Tofanol 5 mg may include: 
  • Upper respiratory tract infections (common cold, sinus infections)
  • Headache
  • Diarrhea
  • Sore throat and runny or stuffy nose (nasopharyngitis)
  • Increased blood pressure
  • Acne 
Important Warnings and Precautions
Serious side effects can occur, including an increased risk of serious infections (e.g., tuberculosis, shingles), blood clots, and certain cancers. 
  • Infections: This medication decreases the immune system’s activity, making it harder to fight infections. Patients should be tested for tuberculosis before starting treatment and monitored during therapy.
  • Blood Clots: There is an increased risk of developing blood clots in the legs or lungs, particularly in older patients with cardiovascular risk factors.
  • Pregnancy/Breastfeeding: Tofanol 5 mg is generally not recommended during pregnancy or breastfeeding.
  • Monitoring: Regular blood tests are necessary to monitor liver function, kidney function, blood counts, and cholesterol levels during treatment. 
Always consult with a healthcare professional before starting or stopping this medication. 

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