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Tofanol 5 mg tablets contain the active ingredient tofacitinib and are primarily used to treat various autoimmune inflammatory disorders. This is a prescription medication that works by modulating the immune system.
Key Information
- Active Ingredient: Tofanol 5 mg tablets contain tofacitinib (5 mg).
- Mechanism of Action: Tofacitinib is a Janus kinase (JAK) inhibitor. It works by blocking the action of JAK enzymes, which are involved in the inflammation that causes symptoms in certain chronic conditions.
- Manufacturer: The manufacturer for the Tofanol brand of tofacitinib is listed as Knoll by several sources.
- Prescription Status: This medication is a prescription drug and should be used under medical supervision.
Uses
Tofanol 5 mg is used to treat moderate to severe forms of the following conditions, typically in adults who have not responded well to other therapies like TNF inhibitors:
- Rheumatoid arthritis: A condition causing pain, swelling, and loss of joint function.
- Psoriatic arthritis: A type of arthritis that affects some individuals with psoriasis, causing joint pain, stiffness, and swelling.
- Ankylosing spondylitis: A form of arthritis that mainly affects the spine and large joints.
- Ulcerative colitis: A condition causing swelling and sores (ulcers) in the lining of the colon and rectum.
Common Side Effects
Common side effects of Tofanol 5 mg may include:
- Upper respiratory tract infections (common cold, sinus infections)
- Headache
- Diarrhea
- Sore throat and runny or stuffy nose (nasopharyngitis)
- Increased blood pressure
- Acne
Important Warnings and Precautions
Serious side effects can occur, including an increased risk of serious infections (e.g., tuberculosis, shingles), blood clots, and certain cancers.
- Infections: This medication decreases the immune system’s activity, making it harder to fight infections. Patients should be tested for tuberculosis before starting treatment and monitored during therapy.
- Blood Clots: There is an increased risk of developing blood clots in the legs or lungs, particularly in older patients with cardiovascular risk factors.
- Pregnancy/Breastfeeding: Tofanol 5 mg is generally not recommended during pregnancy or breastfeeding.
- Monitoring: Regular blood tests are necessary to monitor liver function, kidney function, blood counts, and cholesterol levels during treatment.
Always consult with a healthcare professional before starting or stopping this medication.
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